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doi: 10.1136/jitc-2020-002285 45 RyzhakovGLaiCCBlazekKToKWHussellTUdalovaI

[3] Initial dosing for moderate vasomotor symptoms typically ranges from 1 mg to 5 mg intramuscularly every three to four weeks, with some clinicians favoring a midpoint 2.5 mg monthly regimen and titrating upward or downward according to symptom relief and serum estradiol targets